{"text_format":"3","workbook":"xlsx","n_sheets":52,"sheets":["Validation Summary Report","Instructions","Areas of Trials 1-5","Variance in Instrument Response","Linear Model Equal","Residual Plot Equal","Linear Model 1|x","Linear Curves 1|x","Residual Plot 1|x","Linear Model 1|x^2","Linear Curves 1|x^2","Residual Plot 1|x^2","Linear Model 1|x^0.5","Linear Curves 1|x^0.5","Residual Plot 1|x^0.5","Linear Model 1|y","Linear Curves 1|y","Residual Plot 1|y","Linear Model 1|y^2","Linear Curves 1|y^2","Residual Plot 1|y^2","Linear Model 1|y^0.5","Linear Curves 1|y^0.5","Residual Plot 1|y^0.5","Quadratic Model Equal","Quadratic Residual Plot Equal","Quadratic Model 1|x","Quadratic Curves 1|x","Quadratic Residual Plot 1|x","Quadratic Model 1|x^2","Quadratic Curves 1|x^2","Quadratic Residual Plot 1|x^2","Quadratic Model 1|x^0.5","Quadratic Curves 1|x^0.5","Quadratic Residual Plot 1|x^0.5","Quadratic Model 1|y","Quadratic Curves 1|y","Quadratic Residual Plot 1|y","Quadratic Model 1|y^2","Quadratic Curves 1|y^2","Quadratic Residual Plot 1|y^2","Quadratic Model 1|y^0.5","Quadratic Curves 1|y^0.5","Quadratic Residual Plot 1|y^0.5","LOD","LLOQ","QC","Carryover","Recovery","Dilution Integrity","Ion Suppression","Stability"],"not_rendered":{"charts":52,"macros":1,"defined_names":1201},"read":"row_number_cap","date_system":"1900"}

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["LOD Target:",null,null,{"$f":"0.5*level1","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":0},"Experimental Mean LOD:"]
["Bias",null,null,{"$f":"level1","v":{"v":0,"d":"0.000"}},0,null,"LLOQ"]
[{"$nulls":3},{"$f":"lowqc","v":{"v":0,"d":"0.000"}},0,null,"Low QC"]
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[{"$nulls":3},"Low","Within & Between run ≤ ± 20%",null,"Low QC",null,"Within"]
[{"$nulls":8},"Between"]
[{"$nulls":3},"Medium","Within & Between run ≤ ± 20%",null,"Medium QC",null,"Within"]
[{"$nulls":8},"Between"]
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[{"$f":"A1","v":0}]
[{"$f":"A2","v":0},{"$nulls":4},"ISTD:",{"$f":"ISTD","v":0}]
["Parameter",null,null,"Desired Limit",null,null,"Result"]
["Interference Studies",null,null,"No interfering signals from the matrix, isotopically-labelled internal standards, common drugs of abuse, OTC drugs and prescription medications",null,null,"No interfering signals from the matrix, isotopically-labelled internal standards, common drugs of abuse, OTC drugs and prescription medications."]
["Carryover",null,null,"No significant carryover detected in a blank control analyzed after a L7x10 calibrator fortified sample.",null,null,"L7x1",{"$f":"carryover1","v":"N/A"},{"$f":"unit","v":0}]
[{"$nulls":6},"L7x2",{"$f":"carryover2","v":"N/A"},{"$f":"unit","v":0}]
[{"$nulls":6},"L7x10",{"$f":"carryover10","v":"N/A"},{"$f":"unit","v":0}]
["Recovery",{"$nulls":5},"Low QC"]
[{"$nulls":6},"High QC"]
["Dilution Integrity",null,null,"Accuracy and Precision criteria of ≤ ± 20% met at designated dilution levels",null,null,{"$f":"dilutionfactor1","v":2},null,"Bias"]
[{"$nulls":6},"Precision",null,"Within"]
[{"$nulls":8},"Between"]
[{"$nulls":6},{"$f":"dilutionfactor2","v":5},null,"Bias"]
[{"$nulls":6},"Precision",null,"Within"]
[{"$nulls":8},"Between"]
[{"$nulls":6},{"$f":"dilutionfactor3","v":10},null,"Bias"]
[{"$nulls":6},"Precision",null,"Within"]
[{"$nulls":8},"Between"]
["Ion Suppression/   Enhancement",null,null,"% Ionization Low QC:"]
[{"$nulls":3},"% Ionization ISTD Low QC:"]
[{"$nulls":3},"% Ionization High QC:"]
[{"$nulls":3},"% Ionization ISTD Hi QC:"]
["   "]

{"sheet":"Instructions","index":1,"n_rows":32,"n_cols":1,"rows_kept":32}
["Data entry fields are colored orange and are  filled automatically using the VBA Data Entry forms"]
["Acceptable values will automatically turn blue when values are within defined limits"]
["Cells calculated by the template (editable)"]
[]
["1. Click the \"Data Entry\" button below to begin entering your data.\n1a. If you are importing .csv or .xlsx files - please ensure that all calibration data is located within one subdirectory."]
["2. The workbook will be saved in the specified location that as both an Excel workbook and a PDF."]
["3. If you need to edit any of your data, select the appropriate button below or on the page that you wish to edit."]
["4. If you edit any data, you can save your changes in a PDF by clicking the button below. Clicking this button will overwrite any existing PDF in the specified location."]
["If you've been dreaming about processing method validation data the easy way, you have come to the right place! Dreams do come true, every once in a while, outside of Magic Kingdom!"]
{"$rows_empty":19}
["New in EZSTATSG3:"]
["○  Data importation support for Thermo TraceFinder, Agilent MassHunter, Waters UNIFI, and SCIEX MultiQuant calibration reports"]
["○  Thermo QC report importation supported \n•  Each trial must have it's own folder named \"Trial_1\", \"Trial_2\"... OR \"Trial 1\", \"Trial 2\"... (not case sensitive).\n•  Each individual file name must contain the QC level i.e., \"High\", \"Low\", \"Mid\" (not case sensitive)."]
["○  Color scheme updated for readability"]

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[]
["Drug:"]
["Calibration Model:"]
["Toxicologist(s):",{"$nulls":4},"Instrument:"]
[null,null,"Trial 1"]
["Calibrator Level & Concentration",null,"Drug Response",null,"Internal Standard Response",null,"Area Ratio"]
[]
["L1",{"$nulls":5},{"$f":"C8/E8","v":{"$error":"#DIV/0!"}}]
["L2",{"$nulls":5},{"$f":"IF(OR(ISBLANK(B$9), ISBLANK(C9), ISBLANK(E9)), \"\", C9/E9)","v":""}]
["L3",{"$nulls":5},{"$f":"IF(OR(ISBLANK(B$10), ISBLANK(C10), ISBLANK(E10)), \"\", C10/E10)","v":""}]
["L4",{"$nulls":5},{"$f":"IF(OR(ISBLANK(B$11), ISBLANK(C11), ISBLANK(E11)), \"\", C11/E11)","v":""}]
["L5",{"$nulls":5},{"$f":"IF(OR(ISBLANK(B$12), ISBLANK(C12), ISBLANK(E12)), \"\", C12/E12)","v":""}]
["L6",{"$nulls":5},{"$f":"IF(OR(ISBLANK(B$13), ISBLANK(C13), ISBLANK(E13)), \"\", C13/E13)","v":""}]
["L7",{"$nulls":5},{"$f":"IF(OR(ISBLANK(B$14), ISBLANK(C14), ISBLANK(E14)), \"\", C14/E14)","v":""}]
["n=",{"$f":"COUNT(IF(B8:B14<>0,$B$8:$B$14))","v":0},"Trial 2"]
[{"$f":"A6","v":"Calibrator Level & Concentration"},null,"Drug Response",null,"Internal Standard Response",null,{"$f":"G6","v":"Area Ratio"}]
[null,{"$f":"unit","v":0},{"$f":"analytename","v":0},null,{"$f":"ISTD","v":0}]
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[{"$f":"A1","v":0}]
[{"$f":"A2","v":"Drug:"},{"$f":"'Validation Summary Report'!A2","v":0}]
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[{"$f":"A4","v":"Toxicologist(s):"},{"$nulls":4},{"$f":"F4","v":"Instrument:"},{"$f":"G4","v":0}]
[null,null,"Trial 3"]
[{"$f":"A6","v":"Calibrator Level & Concentration"},null,"Drug Response",null,"Internal Standard Response",null,{"$f":"G6","v":"Area Ratio"}]
[null,{"$f":"unit","v":0},{"$f":"analytename","v":0},null,{"$f":"ISTD","v":0}]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
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[]
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[]
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[]
["Standardized",null,null,"w (1/x)",{"$nulls":3},"Equal",{"$nulls":5},"Standardized"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias","ŷ","w(y-yhat)^2",null,"Residual"]
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["Drug:",{"$f":"analytename","v":0}]
["Unit:",{"$f":"unit","v":0}]
[]
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[]
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[]
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[]
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[]
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[]
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[]
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[]
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[]
["Standardized",null,null,"w (1/x)",{"$nulls":3},"Equal",{"$nulls":5},"Standardized"]
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[]
[]
[]
["Standard Residual",{"$nulls":7},"x","f(x)",null,"Standard Residual",{"$nulls":7},"x","f(x)"]
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[]
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[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
[null,{"$f":"MINVERSE(B73:D75)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
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[]
[null,{"$f":"MINVERSE(B81:D83)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
["Standardized",null,null,"w (1/x2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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["Drug:",{"$f":"analytename","v":0}]
["Unit:",{"$f":"unit","v":0}]
[]
["Trial 3","x","y","w (1/x2)","x2","x3","x4","xy","x2y","(y - y̅)2"]
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[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
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[]
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[]
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[]
["Standardized",null,null,"w (1/x2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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["Drug:",{"$f":"analytename","v":0}]
["Unit:",{"$f":"unit","v":0}]
[]
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[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
[null,{"$f":"MINVERSE(B171:D173)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
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[]
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[]
["Standardized",null,null,"w (1/x2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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["Drug:",{"$f":"analytename","v":0}]
["Unit:",{"$f":"unit","v":0}]
[]
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[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
[null,{"$f":"MINVERSE(B220:D222)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["A-1 =",{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$nulls":3},{"$f":"1-SUMPRODUCT(G238:G244^2)/SUMPRODUCT(J201:J207)","v":{"$error":"#DIV/0!"}},"R2"]
[null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
[null,{"$f":"G218","v":{"$error":"#DIV/0!"}},{"$f":"F218","v":{"$error":"#DIV/0!"}},{"$f":"E218","v":{"$error":"#DIV/0!"}},null,{"$f":"I218","v":{"$error":"#DIV/0!"}},"a",{"$f":"MMULT(B232:D234,F228:F230)","v":{"$error":"#DIV/0!"}},{"$f":"a5_1x2-TINV(0.05,n-3)*SQRT(N230)","v":{"$error":"#DIV/0!"}},{"$f":"a5_1x2+TINV(0.05,n-3)*SQRT(N230)","v":{"$error":"#DIV/0!"}},null,{"$f":"L245*$Y$19:$AA$21","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[null,{"$f":"E218","v":{"$error":"#DIV/0!"}},{"$f":"B218","v":{"$error":"#DIV/0!"}},{"$f":"sumw_1x2","v":{"$error":"#DIV/0!"}},null,{"$f":"C218","v":{"$error":"#DIV/0!"}},"c",{"$error":"#DIV/0!"},{"$f":"see5_1x2-TINV(0.05,n-3)*SQRT(L228)","v":{"$error":"#DIV/0!"}},{"$f":"see5_1x2+TINV(0.05,n-3)*SQRT(L228)","v":{"$error":"#DIV/0!"}},null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
[null,{"$f":"MINVERSE(B228:D230)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
["Standardized",null,null,"w (1/x2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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["","0",{"$f":"IF(ISBLANK(level3), \"\", level3)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level4), \"\", level4)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level5), \"\", level5)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level6), \"\", level6)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level7), \"\", level7)","v":""},"","0","0","0","","","0",null,"0"]
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[]
[]
[]
["Standard Residual",{"$nulls":7},"x","f(x)"]
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["","RANGE",{"$f":"C251-C250","v":{"$error":"#DIV/0!"}},null,{"$f":"E251+$C$254","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},"MEAN -3SD",{"$f":"H250-3*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","# of Bins",10,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},"MEAN + 3SD",{"$f":"H250+3*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Interval",{"$f":"C252/C253","v":{"$error":"#DIV/0!"}},null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},"NO OF BINS",100,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Q1",{"$f":"QUARTILE($A$250:$A$284,1)","v":{"$error":"#DIV/0!"}},{"$f":"_xlfn.NORM.DIST(C255,$H$250,$H$251,FALSE)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},"STEP SIZE",{"$f":"(H253-H252)/H254","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Median",{"$f":"QUARTILE($A$250:$A$284,2)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I91=\"\", \"\", B91/STDEV(B$91:B$97))","v":{"$error":"#DIV/0!"}},"Q3",{"$f":"QUARTILE($A$250:$A$284,3)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I92=\"\", \"\", B92/STDEV(B$91:B$97))","v":""},"-1SD",{"$f":"-H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","1SD",{"$f":"H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
["Standardized",null,null,"w (1/x1/2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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["Drug:",{"$f":"analytename","v":0}]
["Unit:",{"$f":"unit","v":0}]
[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
[null,{"$f":"MINVERSE(B73:D75)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
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[]
[null,{"$f":"MINVERSE(B81:D83)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
["Standardized",null,null,"w (1/x1/2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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["Drug:",{"$f":"analytename","v":0}]
["Unit:",{"$f":"unit","v":0}]
[]
["Trial 3","x","y","w (1/x1/2)","x2","x3","x4","xy","x2y","(y - y̅)2"]
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[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
[null,{"$f":"MINVERSE(B122:D124)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
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[]
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[]
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[]
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[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
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[]
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[]
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[]
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["Unit:",{"$f":"unit","v":0}]
[]
["Trial 5","x","y","w (1/x1/2)","x2","x3","x4","xy","x2y","(y - y̅)2"]
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[]
[null,"wx","wy",null,"wx2","wx3","wx4","wxy","wx2y","(y - y̅w)2"]
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[null,{"$f":"SUM(B211:B217)","v":{"$error":"#DIV/0!"}},{"$f":"SUM(C211:C217)","v":{"$error":"#DIV/0!"}},null,{"$f":"SUM(E211:E217)","v":{"$error":"#DIV/0!"}},{"$f":"SUM(F211:F217)","v":{"$error":"#DIV/0!"}},{"$f":"SUM(G211:G217)","v":{"$error":"#DIV/0!"}},{"$f":"SUM(H211:H217)","v":{"$error":"#DIV/0!"}},{"$f":"SUM(I211:I217)","v":{"$error":"#DIV/0!"}}]
[{"$nulls":8},"95% Confidence Interval"]
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[]
[null,{"$f":"MINVERSE(B220:D222)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["A-1 =",{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$nulls":3},{"$f":"1-SUMPRODUCT(G238:G244^2)/SUMPRODUCT(J201:J207)","v":{"$error":"#DIV/0!"}},"R2"]
[null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
[null,{"$f":"G218","v":{"$error":"#DIV/0!"}},{"$f":"F218","v":{"$error":"#DIV/0!"}},{"$f":"E218","v":{"$error":"#DIV/0!"}},null,{"$f":"I218","v":{"$error":"#DIV/0!"}},"a",{"$f":"MMULT(B232:D234,F228:F230)","v":{"$error":"#DIV/0!"}},{"$f":"a5_1x0.5-TINV(0.05,n-3)*SQRT(N230)","v":{"$error":"#DIV/0!"}},{"$f":"a5_1x0.5+TINV(0.05,n-3)*SQRT(N230)","v":{"$error":"#DIV/0!"}},null,{"$f":"L245*$Y$19:$AA$21","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["A =",{"$f":"F218","v":{"$error":"#DIV/0!"}},{"$f":"E218","v":{"$error":"#DIV/0!"}},{"$f":"B218","v":{"$error":"#DIV/0!"}},"B =",{"$f":"H218","v":{"$error":"#DIV/0!"}},"b",{"$error":"#DIV/0!"},{"$f":"b5_1x0.5-TINV(0.05,n-3)*SQRT(M229)","v":{"$error":"#DIV/0!"}},{"$f":"b5_1x0.5+TINV(0.05,n-3)*SQRT(M229)","v":{"$error":"#DIV/0!"}},"COV=",{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[null,{"$f":"E218","v":{"$error":"#DIV/0!"}},{"$f":"B218","v":{"$error":"#DIV/0!"}},{"$f":"sumw_1x0.5","v":{"$error":"#DIV/0!"}},null,{"$f":"C218","v":{"$error":"#DIV/0!"}},"c",{"$error":"#DIV/0!"},{"$f":"see5_1x0.5-TINV(0.05,n-3)*SQRT(L228)","v":{"$error":"#DIV/0!"}},{"$f":"see5_1x0.5+TINV(0.05,n-3)*SQRT(L228)","v":{"$error":"#DIV/0!"}},null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
[null,{"$f":"MINVERSE(B228:D230)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["A-1 =",{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$nulls":3},{"$f":"1-SUMPRODUCT($D$5:$D$11,B238:B244^2)/SUMPRODUCT($D$5:$D$11,J211:J217)","v":{"$error":"#DIV/0!"}},"R2"]
[null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
["Standardized",null,null,"w (1/x1/2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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["","0",{"$f":"IF(ISBLANK(level3), \"\", level3)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level4), \"\", level4)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level5), \"\", level5)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level6), \"\", level6)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level7), \"\", level7)","v":""},"","0","0","0","","","0",null,"0"]
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[]
[]
[]
["Standard Residual",{"$nulls":7},"x","f(x)"]
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[{"$f":"IF(I43=\"\", \"\", B43/STDEV(B$42:B$48))","v":""},"MAX",{"$f":"QUARTILE($A$250:$A$284,4)","v":{"$error":"#DIV/0!"}},{"$f":"_xlfn.NORM.DIST(C251,$H$250,$H$251,FALSE)","v":{"$error":"#DIV/0!"}},{"$f":"C250","v":{"$error":"#DIV/0!"}},{"$f":"FREQUENCY(A250:A284,E251:E261)","v":{"$error":"#DIV/0!"}},"SD",{"$f":"STDEV($A$250:$A$284)","v":{"$error":"#DIV/0!"}},{"$f":"I250+$H$255","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"}]
["","RANGE",{"$f":"C251-C250","v":{"$error":"#DIV/0!"}},null,{"$f":"E251+$C$254","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},"MEAN -3SD",{"$f":"H250-3*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","# of Bins",10,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},"MEAN + 3SD",{"$f":"H250+3*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Interval",{"$f":"C252/C253","v":{"$error":"#DIV/0!"}},null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},"NO OF BINS",100,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Q1",{"$f":"QUARTILE($A$250:$A$284,1)","v":{"$error":"#DIV/0!"}},{"$f":"_xlfn.NORM.DIST(C255,$H$250,$H$251,FALSE)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},"STEP SIZE",{"$f":"(H253-H252)/H254","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Median",{"$f":"QUARTILE($A$250:$A$284,2)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I91=\"\", \"\", B91/STDEV(B$91:B$97))","v":{"$error":"#DIV/0!"}},"Q3",{"$f":"QUARTILE($A$250:$A$284,3)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I92=\"\", \"\", B92/STDEV(B$91:B$97))","v":""},"-1SD",{"$f":"-H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","1SD",{"$f":"H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","-2SD",{"$f":"-2*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","2SD",{"$f":"2*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Mean",{"$f":"H250","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$nulls":4},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I140=\"\", \"\", B140/STDEV(B$140:B$146))","v":{"$error":"#DIV/0!"}},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I141=\"\", \"\", B141/STDEV(B$140:B$146))","v":""},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I189=\"\", \"\", B189/STDEV(B$189:B$195))","v":{"$error":"#DIV/0!"}},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I190=\"\", \"\", B190/STDEV(B$189:B$195))","v":""},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I238=\"\", \"\", B238/STDEV(B$238:B$244))","v":{"$error":"#DIV/0!"}},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I239=\"\", \"\", B239/STDEV(B$238:B$244))","v":""},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$f":"_xlfn.NORM.DIST(I282,$H$250,$H$251,FALSE)","v":{"$error":"#DIV/0!"}}]
["",{"$nulls":7},{"$f":"I282+$H$255","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
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[]
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[]
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[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
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[]
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[]
[null,{"$f":"MINVERSE(B228:D230)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
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[]
[]
[]
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[]
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[]
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[]
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[]
["Standardized",null,null,"w (1/y2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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["Unit:",{"$f":"unit","v":0},{"$nulls":18},"c","b","a"]
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[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
[null,{"$f":"MINVERSE(B220:D222)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
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[]
[null,{"$f":"MINVERSE(B228:D230)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
["Standardized",null,null,"w (1/y2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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[]
[]
[]
["Standard Residual",{"$nulls":7},"x","f(x)"]
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[]
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[]
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[]
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[{"$nulls":8},"95% Confidence Interval"]
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[]
[null,{"$f":"MINVERSE(B220:D222)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["A-1 =",{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$nulls":3},{"$f":"1-SUMPRODUCT(G238:G244^2)/SUMPRODUCT(J201:J207)","v":{"$error":"#DIV/0!"}},"R2"]
[null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
[null,{"$f":"G218","v":{"$error":"#DIV/0!"}},{"$f":"F218","v":{"$error":"#DIV/0!"}},{"$f":"E218","v":{"$error":"#DIV/0!"}},null,{"$f":"I218","v":{"$error":"#DIV/0!"}},"a",{"$f":"MMULT(B232:D234,F228:F230)","v":{"$error":"#DIV/0!"}},{"$f":"a5_1y0.5-TINV(0.05,n-3)*SQRT(N230)","v":{"$error":"#DIV/0!"}},{"$f":"a5_1y0.5+TINV(0.05,n-3)*SQRT(N230)","v":{"$error":"#DIV/0!"}},null,{"$f":"L245*Y215:AA217","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["A =",{"$f":"F218","v":{"$error":"#DIV/0!"}},{"$f":"E218","v":{"$error":"#DIV/0!"}},{"$f":"B218","v":{"$error":"#DIV/0!"}},"B =",{"$f":"H218","v":{"$error":"#DIV/0!"}},"b",{"$error":"#DIV/0!"},{"$f":"b5_1y0.5-TINV(0.05,n-3)*SQRT(M229)","v":{"$error":"#DIV/0!"}},{"$f":"b5_1y0.5+TINV(0.05,n-3)*SQRT(M229)","v":{"$error":"#DIV/0!"}},"COV=",{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[null,{"$f":"E218","v":{"$error":"#DIV/0!"}},{"$f":"B218","v":{"$error":"#DIV/0!"}},{"$f":"sumw5_1y0.5","v":{"$error":"#DIV/0!"}},null,{"$f":"C218","v":{"$error":"#DIV/0!"}},"c",{"$error":"#DIV/0!"},{"$f":"see5_1y0.5-TINV(0.05,n-3)*SQRT(L228)","v":{"$error":"#DIV/0!"}},{"$f":"see5_1y0.5+TINV(0.05,n-3)*SQRT(L228)","v":{"$error":"#DIV/0!"}},null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
[null,{"$f":"MINVERSE(B228:D230)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["A-1 =",{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$nulls":3},{"$f":"1-SUMPRODUCT(D201:D207,B238:B244^2)/SUMPRODUCT(D201:D207,J211:J217)","v":{"$error":"#DIV/0!"}},"R2"]
[null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
["Standardized",null,null,"w (1/y1/2)",{"$nulls":3},"Equal"]
["Residual","y - ŷ","Target","Calculated","ŷ","Bias","y - ŷ","Calculated","Response","Bias",null,"w(y-yhat)^2"]
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["","0",{"$f":"IF(ISBLANK(level3), \"\", level3)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level4), \"\", level4)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level5), \"\", level5)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level6), \"\", level6)","v":""},"","0","0","0","","","0",null,"0"]
["","0",{"$f":"IF(ISBLANK(level7), \"\", level7)","v":""},"","0","0","0","","","0",null,"0"]
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[]
[]
[]
["Standard Residual",{"$nulls":7},"x","f(x)"]
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[{"$f":"IF(I43=\"\", \"\", B43/STDEV(B$42:B$48))","v":""},"MAX",{"$f":"QUARTILE($A$250:$A$284,4)","v":{"$error":"#DIV/0!"}},{"$f":"_xlfn.NORM.DIST(C251,$H$250,$H$251,FALSE)","v":{"$error":"#DIV/0!"}},{"$f":"C250","v":{"$error":"#DIV/0!"}},{"$f":"FREQUENCY(A250:A284,E251:E261)","v":{"$error":"#DIV/0!"}},"SD",{"$f":"STDEV($A$250:$A$284)","v":{"$error":"#DIV/0!"}},{"$f":"I250+$H$255","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"}]
["","RANGE",{"$f":"C251-C250","v":{"$error":"#DIV/0!"}},null,{"$f":"E251+$C$254","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},"MEAN -3SD",{"$f":"H250-3*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","# of Bins",10,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},"MEAN + 3SD",{"$f":"H250+3*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Interval",{"$f":"C252/C253","v":{"$error":"#DIV/0!"}},null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},"NO OF BINS",100,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Q1",{"$f":"QUARTILE($A$250:$A$284,1)","v":{"$error":"#DIV/0!"}},{"$f":"_xlfn.NORM.DIST(C255,$H$250,$H$251,FALSE)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},"STEP SIZE",{"$f":"(H253-H252)/H254","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Median",{"$f":"QUARTILE($A$250:$A$284,2)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I91=\"\", \"\", B91/STDEV(B$91:B$97))","v":{"$error":"#DIV/0!"}},"Q3",{"$f":"QUARTILE($A$250:$A$284,3)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I92=\"\", \"\", B92/STDEV(B$91:B$97))","v":""},"-1SD",{"$f":"-H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","1SD",{"$f":"H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","-2SD",{"$f":"-2*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","2SD",{"$f":"2*H251","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},null,null,{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["","Mean",{"$f":"H250","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$nulls":4},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I140=\"\", \"\", B140/STDEV(B$140:B$146))","v":{"$error":"#DIV/0!"}},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I141=\"\", \"\", B141/STDEV(B$140:B$146))","v":""},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I189=\"\", \"\", B189/STDEV(B$189:B$195))","v":{"$error":"#DIV/0!"}},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I190=\"\", \"\", B190/STDEV(B$189:B$195))","v":""},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["",{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[{"$f":"IF(I238=\"\", \"\", B238/STDEV(B$238:B$244))","v":{"$error":"#DIV/0!"}},{"$nulls":7},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
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[]
[{"$f":"'Areas of Trials 1-5'!$A$3:$C$3","v":"Calibration Model:"},{"$nulls":3},"Quadratic  (1/y1/2)"]
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[{"$f":"assayname","v":0}]
[{"$f":"'Areas of Trials 1-5'!A2","v":"Drug:"},{"$f":"analytename","v":0}]
["Unit:",{"$f":"unit","v":0}]
["Limit of Detection (LOD) (1 of 1)"]
[{"$f":"'Areas of Trials 1-5'!A4:B4","v":"Toxicologist(s):"},null,null,{"$f":"'Areas of Trials 1-5'!C4","v":0},{"$f":"'Areas of Trials 1-5'!D4","v":0},{"$f":"'Areas of Trials 1-5'!C28","v":0},{"$f":"'Areas of Trials 1-5'!D28","v":0},{"$f":"'Areas of Trials 1-5'!C52","v":0},{"$f":"'Areas of Trials 1-5'!F4","v":"Instrument:"},null,null,{"$f":"'Areas of Trials 1-5'!G4","v":0}]
[]
["Estimated LOD from Linear Calibration Curves"]
[null,"Slope",{"$nulls":6},"y-intercept"]
["Weight","Equal","1/x","1/x2","1/x1/2","1/y","1/y2","1/y1/2","Equal","1/x","1/x2","1/x1/2","1/y","1/y2","1/y1/2"]
["Trial 1",{"$f":"slope1_equal","v":{"$error":"#DIV/0!"}},{"$f":"slope1_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!slope1_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!slope1_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!slope1_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!slope1_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!slope1_1y0.5","v":{"$error":"#DIV/0!"}},{"$f":"intercept1_equal","v":{"$error":"#DIV/0!"}},{"$f":"intercept1_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!intercept1_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!intercept1_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!intercept1_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!intercept1_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!intercept1_1y0.5","v":{"$error":"#DIV/0!"}}]
["Trial 2",{"$f":"slope2_equal","v":{"$error":"#DIV/0!"}},{"$f":"slope2_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!slope2_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!slope2_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!slope2_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!slope2_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!slope2_1y0.5","v":{"$error":"#DIV/0!"}},{"$f":"intercept2_equal","v":{"$error":"#DIV/0!"}},{"$f":"intercept2_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!intercept2_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!intercept2_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!intercept2_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!intercept2_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!intercept2_1y0.5","v":{"$error":"#DIV/0!"}}]
["Trial 3",{"$f":"slope3_equal","v":{"$error":"#DIV/0!"}},{"$f":"slope3_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!slope3_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!slope3_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!slope3_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!slope3_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!slope3_1y0.5","v":{"$error":"#DIV/0!"}},{"$f":"intercept3_equal","v":{"$error":"#DIV/0!"}},{"$f":"intercept3_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!intercept3_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!intercept3_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!intercept3_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!intercept3_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!intercept3_1y0.5","v":{"$error":"#DIV/0!"}}]
["Trial 4",{"$f":"slope4_equal","v":{"$error":"#DIV/0!"}},{"$f":"slope4_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!slope4_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!slope4_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!slope4_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!slope4_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!slope4_1y0.5","v":{"$error":"#DIV/0!"}},{"$f":"intercept4_equal","v":{"$error":"#DIV/0!"}},{"$f":"intercept4_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!intercept4_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!intercept4_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!intercept4_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!intercept4_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!intercept4_1y0.5","v":{"$error":"#DIV/0!"}}]
["Trial 5",{"$f":"slope5_equal","v":{"$error":"#DIV/0!"}},{"$f":"slope5_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!slope5_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!slope5_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!slope5_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!slope5_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!slope5_1y0.5","v":{"$error":"#DIV/0!"}},{"$f":"intercept5_equal","v":{"$error":"#DIV/0!"}},{"$f":"intercept5_1x","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^2'!intercept5_1x2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|x^0.5'!intercept5_1x0.5","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y'!intercept5_1y","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^2'!intercept5_1y2","v":{"$error":"#DIV/0!"}},{"$f":"'Linear Curves 1|y^0.5'!intercept5_1y0.5","v":{"$error":"#DIV/0!"}}]
["Average",{"$f":"AVERAGE(B10:B14)","v":{"$error":"#DIV/0!"}},{"$f":"AVERAGE(C10:C14)","v":{"$error":"#DIV/0!"}},{"$f":"AVERAGE(D10:D14)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
["SD",{"$nulls":7},{"$f":"STDEV(I10:I14)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(J10:J14)","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
["LOD",{"$f":"(3.3)*(I16)/B15","v":{"$error":"#DIV/0!"}},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"},{"$error":"#DIV/0!"}]
[]
["Estimated LOD Using Reference Materials"]
[{"$f":"level1/2","v":{"v":0,"d":"0.000"}},"Trial 1",null,null,"Trial 2",null,"Trial 3",null,"Trial 4",null,null,"Trial 5",null,"Calculated Mean"]
["Replicate 1",{"$nulls":12},{"$f":"AVERAGE(B22:L24)","v":{"$error":"#DIV/0!"}}]
["Replicate 2",{"$nulls":12},"Bias"]
["Replicate 3",{"$nulls":12},{"$f":"((N22-A21)/A21)","v":{"$error":"#DIV/0!"}}]
[]
["Actual LOD"]
[1.5,null,null,"Trial 1",{"$nulls":3},"Trial 2","Trial 3",{"$nulls":4},"Trial 4","Trial 5","Calculated Mean"]
["Replicate 1",{"$nulls":14},{"$f":"AVERAGE(D28:O30)","v":{"$error":"#DIV/0!"}}]
["Replicate 2",{"$nulls":14},"Accuracy"]
["Replicate 3",{"$nulls":14},{"$f":"((P28-A27)/A27)","v":{"$error":"#DIV/0!"}}]

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[{"$f":"assayname","v":0}]
[{"$f":"'Areas of Trials 1-5'!A2","v":"Drug:"},{"$f":"analytename","v":0}]
["Unit:",{"$f":"unit","v":0}]
["Limit of Quantitation (LLOQ) Bias and Precision (1 of 1)"]
[{"$f":"'Areas of Trials 1-5'!A4:B4","v":"Toxicologist(s):"},null,{"$f":"'Areas of Trials 1-5'!C4","v":0},{"$f":"'Areas of Trials 1-5'!D4","v":0},{"$f":"'Areas of Trials 1-5'!C28","v":0},{"$f":"'Areas of Trials 1-5'!D28","v":0},{"$f":"'Areas of Trials 1-5'!C52","v":0},{"$f":"'Areas of Trials 1-5'!G4","v":0}]
[{"$f":"'Areas of Trials 1-5'!A8","v":"L1"}," Concentration"]
[{"$f":"level1","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":0},null,"Trial 1","Trial 2","Trial 3","Trial 4","Trial 5","Calculated Mean"]
["Replicate 1",{"$nulls":7},{"$f":"AVERAGE(D8:H10)","v":{"$error":"#DIV/0!"}},10,null,13]
["Replicate 2",{"$nulls":7},"Bias",11,null,14]
["Replicate 3",{"$nulls":7},{"$f":"(I8-level1)/level1","v":{"$error":"#DIV/0!"}},12,null,15]
[]
["Anova: Single Factor"]
[]
["SUMMARY"]
["Groups","Count","Sum","Average","Variance","SS"]
["Trial 1",{"$f":"replicate","v":3},{"$f":"SUM(D8:D10)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(D8:D10)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(D8:D10)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(D$8:D$10)","v":{"$error":"#NUM!"}}]
["Trial 2",{"$f":"replicate","v":3},{"$f":"SUM(E8:E10)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(E8:E10)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(E8:E10)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(E$8:E$10)","v":{"$error":"#NUM!"}}]
["Trial 3",{"$f":"replicate","v":3},{"$f":"SUM(F8:F10)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(F8:F10)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(F8:F10)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(F8:F10)","v":{"$error":"#NUM!"}}]
["Trial 4",{"$f":"replicate","v":3},{"$f":"SUM(G8:G10)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(G8:G10)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(G8:G10)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(G8:G10)","v":{"$error":"#NUM!"}}]
["Trial 5",{"$f":"replicate","v":3},{"$f":"SUM(H8:H10)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(H8:H10)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(H8:H10)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(H8:H10)","v":{"$error":"#NUM!"}}]
[]
["ANOVA"]
["Source of Variation","SS","df","MS","F","P-value","F crit"]
["Between Groups",{"$f":"DEVSQ(C16:C20)/B16","v":{"v":0,"d":"0.00E+00"}},{"$f":"trial-1","v":4},{"$f":"B24/C24","v":{"v":0,"d":"0.00E+00"}},{"$f":"D24/D25","v":{"$error":"#NUM!"}},{"$f":"FDIST(E24,C24,C25)","v":{"$error":"#NUM!"}},{"$f":"FINV(0.05,C24,C25)","v":{"v":3.478049690765228,"d":"3.48E+00"}}]
["Within Groups",{"$f":"SUM(F16:F20)","v":{"$error":"#NUM!"}},{"$f":"replicate*trial-trial","v":10},{"$f":"B25/C25","v":{"$error":"#NUM!"}}]
[]
["Total",{"$f":"SUM(B24:B25)","v":{"$error":"#NUM!"}},{"$f":"SUM(C24:C25)","v":14}]
[]
["Within Run CV (%)",null,{"$f":"SQRT(D25)/I8","v":{"$error":"#NUM!"}}]
["Between Run CV (%)",null,{"$f":"SQRT((D24+(B16-1)*D25)/B16)/I8","v":{"$error":"#NUM!"}}]

{"sheet":"QC","index":46,"n_rows":114,"n_cols":9,"rows_kept":114,"merged":[[0,0,0,8],[1,1,1,8],[3,0,3,2],[4,0,4,1],[4,7,4,8],[8,0,8,2],[9,0,9,2],[10,0,10,2],[14,0,14,2],[15,0,15,2],[16,0,16,2],[20,0,20,2],[21,0,21,2],[22,0,22,2],[26,0,26,2],[27,0,27,2],[30,0,30,8],[31,1,31,8],[33,0,33,3],[34,0,34,1],[34,7,34,8],[36,0,36,3],[56,0,56,1],[57,0,57,1],[58,0,58,8],[59,1,59,8],[61,0,61,3],[62,0,62,1],[62,7,62,8],[64,0,64,3],[84,0,84,1],[85,0,85,1],[86,0,86,8],[87,1,87,8],[89,0,89,4],[90,0,90,1],[90,7,90,8],[92,0,92,3],[112,0,112,1],[113,0,113,1]]}
[{"$f":"assayname","v":0}]
[{"$f":"'Areas of Trials 1-5'!A2","v":"Drug:"},{"$f":"analytename","v":0}]
["Unit:",{"$f":"unit","v":0}]
["QC Bias (1 of 1)"]
[{"$f":"'Areas of Trials 1-5'!A4:B4","v":"Toxicologist(s):"},null,{"$f":"'Areas of Trials 1-5'!$C$4","v":0},{"$f":"'Areas of Trials 1-5'!$D$4","v":0},{"$f":"'Areas of Trials 1-5'!$C$28","v":0},{"$f":"'Areas of Trials 1-5'!$D$28","v":0},{"$f":"'Areas of Trials 1-5'!$C$52","v":0},{"$f":"'Areas of Trials 1-5'!G4","v":0}]
[]
[" Low QC",null," ŷ1"]
[{"$f":"level1*3","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":0},{"$f":"slope1_1x*lowqc+intercept1_1x","v":{"$error":"#DIV/0!"}},"Trial 1","Trial 2","Trial 3","Trial 4","Trial 5","Calculated Mean"]
["Replicate 1",{"$nulls":7},{"$f":"AVERAGE(D9:H11)","v":{"$error":"#DIV/0!"}}]
["Replicate 2",{"$nulls":7},"Bias"]
["Replicate 3",{"$nulls":7},{"$f":"((I9-lowqc)/lowqc)","v":{"$error":"#DIV/0!"}}]
[]
["Mid QC",null," ŷ1"]
[{"$f":"IF(level7<>\"\",level7*0.45,IF(AND(level7=\"\",level6=\"\"),level5*0.45,level6*0.45))","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":0},{"$f":"slope1_1x*mediumqc+intercept1_1x","v":{"$error":"#DIV/0!"}},"Trial 1","Trial 2","Trial 3","Trial 4","Trial 5","Calculated Mean"]
["Replicate 1",{"$nulls":7},{"$f":"AVERAGE(D15:H17)","v":{"$error":"#DIV/0!"}}]
["Replicate 2",{"$nulls":7},"Bias"]
["Replicate 3",{"$nulls":7},{"$f":"((I15-mediumqc)/mediumqc)","v":{"$error":"#DIV/0!"}}]
[]
["High QC",null," ŷ1"]
[{"$f":"IF(level7<>\"\",level7*0.875,IF(AND(level7=\"\",level6=\"\"),level5*0.875,level6*0.875))","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":0},{"$f":"slope1_1x*highqc+intercept1_1x","v":{"$error":"#DIV/0!"}},"Trial 1","Trial 2","Trial 3","Trial 4","Trial 5","Calculated Mean"]
["Replicate 1",{"$nulls":7},{"$f":"AVERAGE(D21:H23)","v":{"$error":"#DIV/0!"}}]
["Replicate 2",{"$nulls":7},"Bias"]
["Replicate 3",{"$nulls":7},{"$f":"((I21-highqc)/highqc)","v":{"$error":"#DIV/0!"}}]
[]
[]
[]
["Replicate Number:",null,null,3]
["Number of Trials:",null,null,5]
[]
[]
[{"$f":"'Validation Summary Report'!A1:J1","v":0}]
["Drug:",{"$f":"'Areas of Trials 1-5'!B2:H2","v":0}]
["Unit:",{"$f":"unit","v":0}]
["QC Precision (1 of 3)"]
[{"$f":"A5","v":"Toxicologist(s):"},null,{"$f":"'Areas of Trials 1-5'!$C$4","v":0},{"$f":"'Areas of Trials 1-5'!$D$4","v":0},{"$f":"'Areas of Trials 1-5'!$C$28","v":0},{"$f":"'Areas of Trials 1-5'!$D$28","v":0},{"$f":"'Areas of Trials 1-5'!$C$52","v":0},{"$f":"H5","v":0}]
[]
[{"$f":"A7","v":" Low QC"},{"$nulls":3},{"$f":"lowqc","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":0}]
[]
["Anova: Single Factor"]
[]
["SUMMARY"]
["Groups","Count","Sum","Average","Variance","SS"]
["Trial 1",{"$f":"replicate","v":3},{"$f":"SUM(D$9:D$11)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(D$9:D$11)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(D$9:D$11)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(D$9:D$11)","v":{"$error":"#NUM!"}}]
["Trial 2",{"$f":"replicate","v":3},{"$f":"SUM(E$9:E$11)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(E$9:E$11)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(E$9:E$11)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(E$9:E$11)","v":{"$error":"#NUM!"}}]
["Trial 3",{"$f":"replicate","v":3},{"$f":"SUM(F$9:F$11)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(F$9:F$11)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(F$9:F$11)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(F$9:F$11)","v":{"$error":"#NUM!"}}]
["Trial 4",{"$f":"replicate","v":3},{"$f":"SUM(G$9:G$11)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(G$9:G$11)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(G$9:G$11)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(G$9:G$11)","v":{"$error":"#NUM!"}}]
["Trial 5",{"$f":"replicate","v":3},{"$f":"SUM(H$9:H$11)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(H$9:H$11)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(H$9:H$11)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(H$9:H$11)","v":{"$error":"#NUM!"}}]
[]
[]
["ANOVA"]
["Source of Variation","SS","df","MS","F","P-value","F crit"]
["Between Groups",{"$f":"DEVSQ(C43:C47)/B43","v":{"v":0,"d":"0.00E+00"}},{"$f":"trial-1","v":4},{"$f":"B52/C52","v":{"v":0,"d":"0.00E+00"}},{"$f":"D52/D53","v":{"$error":"#NUM!"}},{"$f":"FDIST(E52,C52,C53)","v":{"$error":"#NUM!"}},{"$f":"FINV(0.05,C52,C53)","v":{"v":3.478049690765228,"d":"3.48E+00"}}]
["Within Groups",{"$f":"SUM(F43:F47)","v":{"$error":"#NUM!"}},{"$f":"replicate*trial-trial","v":10},{"$f":"B53/C53","v":{"$error":"#NUM!"}}]
[]
["Total",{"$f":"SUM(B52:B53)","v":{"$error":"#NUM!"}},{"$f":"SUM(C52:C53)","v":14}]
[]
["Within Run CV (%)",null,{"$f":"(SQRT(D53)/I9)","v":{"$error":"#NUM!"}}]
["Between Run CV (%)",null,{"$f":"SQRT((D52+(B43-1)*D53)/B43)/I9","v":{"$error":"#NUM!"}}]
[{"$f":"'Validation Summary Report'!A1:J1","v":0}]
["Drug:",{"$f":"'Areas of Trials 1-5'!B2:H2","v":0}]
["Unit:",{"$f":"unit","v":0}]
["QC Precision (2 of 3)"]
[{"$f":"A35","v":"Toxicologist(s):"},null,{"$f":"'Areas of Trials 1-5'!$C$4","v":0},{"$f":"'Areas of Trials 1-5'!$D$4","v":0},{"$f":"'Areas of Trials 1-5'!$C$28","v":0},{"$f":"'Areas of Trials 1-5'!$D$28","v":0},{"$f":"'Areas of Trials 1-5'!$C$52","v":0},{"$f":"'Areas of Trials 1-5'!G4","v":0}]
[]
[{"$f":"A13","v":"Mid QC"},{"$nulls":3},{"$f":"mediumqc","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":0}]
[]
["Anova: Single Factor"]
[]
["SUMMARY"]
["Groups","Count","Sum","Average","Variance","SS"]
["Trial 1",{"$f":"replicate","v":3},{"$f":"SUM(D$15:D$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(D$15:D$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(D$15:D$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(D$15:D$17)","v":{"$error":"#NUM!"}}]
["Trial 2",{"$f":"replicate","v":3},{"$f":"SUM(E$15:E$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(E$15:E$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(E$15:E$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(E$15:E$17)","v":{"$error":"#NUM!"}}]
["Trial 3",{"$f":"replicate","v":3},{"$f":"SUM(F$15:F$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(F$15:F$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(F$15:F$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(F$15:F$17)","v":{"$error":"#NUM!"}}]
["Trial 4",{"$f":"replicate","v":3},{"$f":"SUM(G$15:G$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(G$15:G$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(G$15:G$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(G$15:G$17)","v":{"$error":"#NUM!"}}]
["Trial 5",{"$f":"replicate","v":3},{"$f":"SUM(H$15:H$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(H$15:H$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(H$15:H$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(H$15:H$17)","v":{"$error":"#NUM!"}}]
[]
[]
["ANOVA"]
["Source of Variation","SS","df","MS","F","P-value","F crit"]
["Between Groups",{"$f":"DEVSQ(C71:C75)/B71","v":{"v":0,"d":"0.00E+00"}},{"$f":"trial-1","v":4},{"$f":"B80/C80","v":{"v":0,"d":"0.00E+00"}},{"$f":"D80/D81","v":{"$error":"#NUM!"}},{"$f":"FDIST(E80,C80,C81)","v":{"$error":"#NUM!"}},{"$f":"FINV(0.05,C80,C81)","v":{"v":3.478049690765228,"d":"3.48E+00"}}]
["Within Groups",{"$f":"SUM(F71:F75)","v":{"$error":"#NUM!"}},{"$f":"replicate*trial-trial","v":10},{"$f":"B81/C81","v":{"$error":"#NUM!"}}]
[]
["Total",{"$f":"SUM(B80:B81)","v":{"$error":"#NUM!"}},{"$f":"SUM(C80:C81)","v":14}]
[]
["Within Run CV (%)",null,{"$f":"(SQRT(D81)/I15)","v":{"$error":"#NUM!"}}]
["Between Run CV (%)",null,{"$f":"SQRT((D80+(B71-1)*D81)/B71)/I15","v":{"$error":"#NUM!"}}]
[{"$f":"'Validation Summary Report'!A1:J1","v":0}]
["Drug:",{"$f":"'Areas of Trials 1-5'!B2:H2","v":0}]
["Unit:",{"$f":"unit","v":0}]
["QC Precision (3 of 3)"]
[{"$f":"'Areas of Trials 1-5'!A4:B4","v":"Toxicologist(s):"},null,{"$f":"'Areas of Trials 1-5'!$C$4","v":0},{"$f":"'Areas of Trials 1-5'!$D$4","v":0},{"$f":"'Areas of Trials 1-5'!$C$28","v":0},{"$f":"'Areas of Trials 1-5'!$D$28","v":0},{"$f":"'Areas of Trials 1-5'!$C$52","v":0},{"$f":"'Areas of Trials 1-5'!G4","v":0}]
[]
[{"$f":"A19","v":"High QC"},{"$nulls":3},{"$f":"highqc","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":0}]
[]
["Anova: Single Factor"]
[]
["SUMMARY"]
["Groups","Count","Sum","Average","Variance","SS"]
["Trial 1",{"$f":"replicate","v":3},{"$f":"SUM(D$21:D$23)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(D$21:D$23)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(D$21:D$23)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(D$21:D$23)","v":{"$error":"#NUM!"}}]
["Trial 2",{"$f":"replicate","v":3},{"$f":"SUM(E$21:E$23)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(E$21:E$23)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(E$21:E$23)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(E$21:E$23)","v":{"$error":"#NUM!"}}]
["Trial 3",{"$f":"replicate","v":3},{"$f":"SUM(F$21:F$23)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(F$21:F$23)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(F$21:F$23)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(F$21:F$23)","v":{"$error":"#NUM!"}}]
["Trial 4",{"$f":"replicate","v":3},{"$f":"SUM(G$21:G$23)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(G$21:G$23)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(G$21:G$23)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(G$21:G$23)","v":{"$error":"#NUM!"}}]
["Trial 5",{"$f":"replicate","v":3},{"$f":"SUM(H$21:H$23)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE(H$21:H$23)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV(H$21:H$23)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ(H$21:H$23)","v":{"$error":"#NUM!"}}]
[]
[]
["ANOVA"]
["Source of Variation","SS","df","MS","F","P-value","F crit"]
["Between Groups",{"$f":"DEVSQ(C99:C103)/B99","v":{"v":0,"d":"0.00E+00"}},{"$f":"trial-1","v":4},{"$f":"B108/C108","v":{"v":0,"d":"0.00E+00"}},{"$f":"D108/D109","v":{"$error":"#NUM!"}},{"$f":"FDIST(E108,C108,C109)","v":{"$error":"#NUM!"}},{"$f":"FINV(0.05,C108,C109)","v":{"v":3.478049690765228,"d":"3.48E+00"}}]
["Within Groups",{"$f":"SUM(F99:F103)","v":{"$error":"#NUM!"}},{"$f":"replicate*trial-trial","v":10},{"$f":"B109/C109","v":{"$error":"#NUM!"}}]
[]
["Total",{"$f":"SUM(B108:B109)","v":{"$error":"#NUM!"}},{"$f":"SUM(C108:C109)","v":14}]
[]
["Within Run CV (%)",null,{"$f":"(SQRT(D109)/I21)","v":{"$error":"#NUM!"}}]
["Between Run CV (%)",null,{"$f":"SQRT((D108+(B99-1)*D109)/B99)/I21","v":{"$error":"#NUM!"}}]

{"sheet":"Carryover","index":47,"n_rows":28,"n_cols":9,"rows_kept":28,"merged":[[0,0,0,8],[1,1,1,8],[2,0,2,2],[3,0,3,1],[3,7,3,8],[5,5,5,6],[6,3,6,4],[6,6,6,7],[7,0,7,2],[7,3,7,4],[7,6,7,7],[8,0,8,2],[8,3,8,4],[9,0,9,2],[9,3,9,4],[10,0,10,2],[10,3,10,4],[11,0,11,2],[11,3,11,4],[14,3,14,4],[14,6,14,7],[15,0,15,2],[15,3,15,4],[15,6,15,7],[16,0,16,2],[16,3,16,4],[17,0,17,2],[17,3,17,4],[18,0,18,2],[18,3,18,4],[19,0,19,2],[19,3,19,4],[22,3,22,4],[22,6,22,7],[23,0,23,2],[23,3,23,4],[23,6,23,7],[24,0,24,2],[24,3,24,4],[25,0,25,2],[25,3,25,4],[26,0,26,2],[26,3,26,4],[27,0,27,2],[27,3,27,4]]}
[{"$f":"assayname","v":0}]
[{"$f":"'Areas of Trials 1-5'!A2","v":"Drug:"},{"$f":"analytename","v":0}]
["Carryover (1 of 1)"]
[{"$f":"'Areas of Trials 1-5'!A4:B4","v":"Toxicologist(s):"},null,{"$f":"'Areas of Trials 1-5'!$C$4","v":0},{"$f":"'Areas of Trials 1-5'!$D$4","v":0},{"$f":"'Areas of Trials 1-5'!$C$28","v":0},{"$f":"'Areas of Trials 1-5'!$D$28","v":0},{"$f":"'Areas of Trials 1-5'!$C$52","v":0},{"$f":"'Areas of Trials 1-5'!G4","v":0}]
[]
["L7 Concentration:",{"$nulls":3},"X 1"]
[{"$f":"level7","v":0},{"$f":"unit","v":0},null,"Concentration in Blank",null,null,"Maximum"]
["Trial 1",{"$nulls":5},{"$f":"IF(ISBLANK(D8), \"N/A\", MAX(D8:E12))","v":"N/A"},null,{"$f":"unit","v":0}]
["Trial 2"]
["Trial 3"]
["Trial 4"]
["Trial 5"]
[]
[{"$f":"A6","v":"L7 Concentration:"},{"$nulls":3},"X 2"]
[{"$f":"level7*2","v":0},{"$f":"unit","v":0},null,"Concentration in Blank",null,null,"Maximum"]
["Trial 1",{"$nulls":5},{"$f":"IF(ISBLANK(D16), \"N/A\", MAX(D16:E20))","v":"N/A"},null,{"$f":"unit","v":0}]
["Trial 2"]
["Trial 3"]
["Trial 4"]
["Trial 5"]
[]
[{"$f":"A6","v":"L7 Concentration:"},{"$nulls":3},"X 10"]
[{"$f":"level7*10","v":0},{"$f":"unit","v":0},null,"Concentration in Blank",null,null,"Maximum"]
["Trial 1",{"$nulls":5},{"$f":"IF(ISBLANK(D24), \"N/A\", MAX(D24:E28))","v":"N/A"},null,{"$f":"unit","v":0}]
["Trial 2"]
["Trial 3"]
["Trial 4"]
["Trial 5"]

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[{"$f":"assayname","v":0}]
[{"$f":"'Areas of Trials 1-5'!A2","v":"Drug:"},{"$f":"analytename","v":0}]
["Recovery (1 of 1)"]
[{"$f":"'Areas of Trials 1-5'!A4:B4","v":"Toxicologist(s):"},null,{"$f":"'Areas of Trials 1-5'!$C$4","v":0},{"$f":"'Areas of Trials 1-5'!$D$4","v":0},{"$f":"'Areas of Trials 1-5'!$C$28","v":0},{"$f":"'Areas of Trials 1-5'!$D$28","v":0},{"$f":"'Areas of Trials 1-5'!$C$52","v":0},{"$f":"'Areas of Trials 1-5'!G4","v":0}]
[]
[{"$f":"conclowqc","v":" Low QC"}]
[{"$f":"lowqc","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":{"v":0,"d":"0.000"}},"Extracted Drug Response",null,null,"Unextracted Drug Response"]
["Trial 1"]
["Trial 2"]
["Trial 3"]
["Trial 4"]
["Trial 5"]
[]
["Average",null,null,{"$f":"AVERAGE(D8:D12)","v":{"$error":"#DIV/0!"}},null,null,{"$f":"AVERAGE(G8:G12)","v":{"$error":"#DIV/0!"}}]
["Standard Deviation",null,null,{"$f":"STDEV(D8:D12)","v":{"$error":"#DIV/0!"}},null,null,{"$f":"STDEV(G8:G12)","v":{"$error":"#DIV/0!"}}]
[]
["% Recovery Low QC",null,{"$f":"D14/G14","v":{"$error":"#DIV/0!"}}]
[]
[{"$f":"conchiqc","v":"High QC"}]
[{"$f":"highqc","v":{"v":0,"d":"0.000"}},{"$f":"unit","v":{"v":0,"d":"0.000"}},"Extracted Drug Response",null,null,"Unextracted Drug Response"]
["Trial 1"]
["Trial 2"]
["Trial 3"]
["Trial 4"]
["Trial 5"]
[]
["Average",null,null,{"$f":"AVERAGE(D21:D25)","v":{"$error":"#DIV/0!"}},null,null,{"$f":"AVERAGE(G21:G25)","v":{"$error":"#DIV/0!"}}]
["Standard Deviation",null,null,{"$f":"STDEV(D21:D25)","v":{"$error":"#DIV/0!"}},null,null,{"$f":"STDEV(G21:G25)","v":{"$error":"#DIV/0!"}}]
[]
["% Recovery Hi QC",null,{"$f":"D27/G27","v":{"$error":"#DIV/0!"}}]

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[{"$f":"assayname","v":0}]
[{"$f":"'Areas of Trials 1-5'!A2","v":"Drug:"},{"$f":"analytename","v":0}]
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[]
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[]
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[]
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[]
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[]
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[]
["SUMMARY"]
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["Trial 4",{"$f":"replicate","v":3},{"$f":"SUM(G$9:G$11)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($G$9:$G$11)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($G$9:$G$11)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($G$9:$G$11)","v":{"$error":"#NUM!"}}]
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[]
[]
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["Within Groups",{"$f":"SUM(F45:F49)","v":{"$error":"#NUM!"}},{"$f":"replicate*trial-trial","v":10},{"$f":"B55/C55","v":{"$error":"#NUM!"}}]
[]
["Total",{"$f":"SUM(B54:B55)","v":{"$error":"#NUM!"}},{"$f":"SUM(C54:C55)","v":14}]
[]
["Within Run CV (%)",null,{"$f":"(SQRT(D55)/I9)","v":{"$error":"#NUM!"}}]
["Between Run CV (%)",null,{"$f":"SQRT((D54+(B45-1)*D55)/B45)/I9","v":{"$error":"#NUM!"}}]
[]
[]
[]
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[{"$f":"A2","v":"Drug:"},{"$f":"'Areas of Trials 1-5'!B2:H2","v":0}]
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["Dilution Integrity Precision (2 of 3)"]
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[]
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[]
["Anova: Single Factor"]
[]
["SUMMARY"]
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["Trial 1",{"$f":"replicate","v":3},{"$f":"SUM(D$15:D$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($D$15:$D$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($D$15:$D$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($D$15:$D$17)","v":{"$error":"#NUM!"}}]
["Trial 2",{"$f":"replicate","v":3},{"$f":"SUM(E$15:E$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($E$15:$E$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($E$15:$E$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($E$15:$E$17)","v":{"$error":"#NUM!"}}]
["Trial 3",{"$f":"replicate","v":3},{"$f":"SUM(F$15:F$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($F$15:$F$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($F$15:$F$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($F$15:$F$17)","v":{"$error":"#NUM!"}}]
["Trial 4",{"$f":"replicate","v":3},{"$f":"SUM(G$15:G$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($G$15:$G$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($G$15:$G$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($G$15:$G$17)","v":{"$error":"#NUM!"}}]
["Trial 5",{"$f":"replicate","v":3},{"$f":"SUM(H$15:H$17)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($H$15:$H$17)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($H$15:$H$17)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($H$15:$H$17)","v":{"$error":"#NUM!"}}]
[]
[]
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["Within Groups",{"$f":"SUM(F76:F80)","v":{"$error":"#NUM!"}},{"$f":"replicate*trial-trial","v":10},{"$f":"B86/C86","v":{"$error":"#NUM!"}}]
[]
["Total",{"$f":"SUM(B85:B86)","v":{"$error":"#NUM!"}},{"$f":"SUM(C85:C86)","v":14}]
[]
["Within Run CV (%)",null,{"$f":"(SQRT(D86)/I15)","v":{"$error":"#NUM!"}}]
["Between Run CV (%)",null,{"$f":"SQRT((D85+(B76-1)*D86)/B76)/I15","v":{"$error":"#NUM!"}}]
[]
[]
[]
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[{"$f":"A2","v":"Drug:"},{"$f":"'Areas of Trials 1-5'!B2:H2","v":0}]
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["Dilution Integrity Precision (3 of 3)"]
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[]
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[]
["Anova: Single Factor"]
[]
["SUMMARY"]
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["Trial 2",{"$f":"replicate","v":3},{"$f":"SUM($E$21:$E$23)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($E$21:$E$23)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($E$21:$E$23)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($E$21:$E$23)","v":{"$error":"#NUM!"}}]
["Trial 3",{"$f":"replicate","v":3},{"$f":"SUM($F$21:$F$23)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($F$21:$F$23)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($F$21:$F$23)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($F$21:$F$23)","v":{"$error":"#NUM!"}}]
["Trial 4",{"$f":"replicate","v":3},{"$f":"SUM($G$21:$G$23)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($G$21:$G$23)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($G$21:$G$23)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($G$21:$G$23)","v":{"$error":"#NUM!"}}]
["Trial 5",{"$f":"replicate","v":3},{"$f":"SUM($H$21:$H$23)","v":{"v":0,"d":"0.00E+00"}},{"$f":"AVERAGE($H$21:$H$23)","v":{"$error":"#DIV/0!"}},{"$f":"STDEV($H$21:$H$23)^2","v":{"$error":"#DIV/0!"}},{"$f":"DEVSQ($H$21:$H$23)","v":{"$error":"#NUM!"}}]
[]
[]
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["Within Groups",{"$f":"SUM(F107:F111)","v":{"$error":"#NUM!"}},{"$f":"replicate*trial-trial","v":10},{"$f":"B117/C117","v":{"$error":"#NUM!"}}]
[]
["Total",{"$f":"SUM(B116:B117)","v":{"$error":"#NUM!"}},{"$f":"SUM(C116:C117)","v":14}]
[]
["Within Run CV (%)",null,{"$f":"(SQRT(D117)/I21)","v":{"$error":"#NUM!"}}]
["Between Run CV (%)",null,{"$f":"SQRT((D116+(B107-1)*D117)/B107)/I21","v":{"$error":"#NUM!"}}]

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[]
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[]
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